Open access
Peer reviewed journal

Actual Gynecology
and Obstetrics


Very low incidence of infections after cesarean section with prophylactic antibiotics after cord clamping
Miroslav Gregor
Actual Gyn 2021, 13, 36-42
Publication date: 2021-08-18
Manuscript ID: 1321006
Počet zobrazení: 7226

Objective: The optimal timing of prophylactic antibiotics in women undergoing cesarean section (CS) remains uncertain. Prophylactic antibiotics are beneficial for the mother, but it is proven that antibiotics given before cord clamping can affect the infant's gut bacterial flora, with the potential to impact systemic immune function. Additionally, prophylactic antibiotics may lead to increased drug resistant organisms. This study aimed to assess the effects of giving the antibiotics after the cord is clamped on the incidence of infections after CS. 

Methods: A prospective study involving pregnant woman who underwent CS from January to June 2013 at a tertiary referral center in the Czech Republic. The procedures were done in accordance with the criteria of the Center for Disease Control and Prevention with a follow-up period of 30 days. 

Results: Ten patients (3.3%) had a postcesarean infection. Nine infections were surgical site infections (SSIs) and one was non-surgical site infections (non-SSIs). SSIs included 4 superficial, no deep, and 5 organ/space SSIs. 80% were diagnosed after hospital discharge. One woman’s condition resolved without antibiotics, seven with antibiotics, and two required reoperation with antibiotics. 

Conclusion: In this study timing of administration of prophylactic antibiotics after cord clamping was safe for the baby and efficient for the mother with a low rates of postcesarean infections. 

Key words: infections after cesarean section, antibiotic resistance, prophylactic antibiotics