Open access
Peer reviewed journal

Actual Gynecology
and Obstetrics


Palliative MRI-guided intensity modulated radiation therapy (IMRT) for locally recurrent endometrial cancer
Yukihiro Hama, Etsuko Tate
Actual Gyn 2020, 12, 70-74
Publication date: 2020-12-14
Manuscript ID: 1220020
Počet zobrazení: 7584

Treatment of local recurrence after resection of endometrial cancer is complicated. MRI-guided intensity modulated radiation therapy (IMRT) can deliver high doses of radiation to tumors while sparing the surrounding normal tissues. Here, we report a case of 64-year-old woman with local recurrence and small lung metastases after resection of early endometrial cancer. Since the patient refused chemotherapy, high-dose MRI-guided IMRT (66 Gy in 33 fractions with a maximum of 82 Gy) was performed to alleviate dysuria and hematuria. Her post-treatment course was uneventful and her symptoms resolved after 1 month of treatment. MRI demonstrated that the locally recurrent tumor disappeared completely 6 months after IMRT, and the condition persisted 1 year later. In conclusions, this is the first report of MRI-guided IMRT for locally recurrent endometrial cancer after resection. High-dose MRI-guided IMRT leads to relief of symptoms by controlling local recurrence, and the treatment-related toxicity was minimal.

Key words: endometrial cancer, recurrence, radiotherapy, support therapy