CIN 1-3 or Low-Grade and High-Grade Squamous Lesions? A cytopathologist´s view on the recent proposal of the changes in cervical precanceroses classification. (article in Czech)
The function of diagnostic terminology in any morphology method is to provide information to the clinical specialist that is interpreted unequivocally and which enables him to choose the appropriate treatment.
The former Papanicolaou five-tiered cytological classification of dysplastic changes on the uterine cervix has been simplified to a two-tiered approach.
In the histopathological evaluation, fusion of the categories CIN III and CIS was rather smooth. Further progress toward simplification of the histopathology terminology is proceeding more slowly. The proposed two-tiered classification of the histopathological lesions of the cervix has the potential to create a more precise communication between the clinician and the pathologist in the evaluation and subsequently in the treatment of the cervical lesions. In comparison to the previous classifications, it is fully convertible. It preserves the previous limits in the evaluation of the histopathological finding, mainly the dependence on the primary representativeness of the specimen. Deeper understanding of the cervical cancerogenesis will be achieved with the increasing spectrum of prognostication markers. Thus the tailored treatment of cervical lesion will be enabled.
Key words: classification of the cervical dysplasia, high-grade and low-grade lesions, CIN I - CIN III, three-tiered classification of the cervical dysplasia, two-tiered classification of the cervical dysplasia