Preeclampsia is a multiorgan disease of unclear aetiology typically occurring during pregnancy and having a major share in maternal and neonatal morbidity and mortality. As a result, it has been the subject of a number of studies. The article outlines certain aspects of the disease and deals with the possibilities of its prediction and prevention existing today. Its aim is to assess the clinical practice concerning preeclampsia screening in out-patient department. Although the number of included patients is not high, this study has shown that preeclampsia screening is effective.